Case Reports in Arterial Stiffness

Case Reports in Arterial Stiffness

Arterial stiffness is an important marker of cardiovascular aging, vascular dysfunction, and long-term morbidity. It is increasingly recognized in patients with hypertension, diabetes, chronic kidney disease, connective tissue disorders, and cardiometabolic syndromes. Publishing high-quality case reports helps clinicians understand rare presentations, novel diagnostic techniques, and unique management approaches related to increased arterial stiffness.

The Case Reports and Case Series in Cardiology Journal welcomes submissions featuring unique, informative, and clinically significant cases related to arterial stiffness.

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Scope of Arterial Stiffness Case Reports We Publish

1. Etiologies and Associated Conditions

• Hypertension-related arterial stiffness

• Diabetes mellitus and metabolic syndrome–related stiffness

• Chronic kidney disease (CKD)–associated vascular calcification

• Connective tissue disorders (Marfan, Ehlers-Danlos)

• Aging-related vascular stiffening

• Inflammatory and autoimmune diseases causing arterial changes

• Radiation-induced arterial stiffness

2. Diagnostic Methods

• Pulse wave velocity (PWV)–based diagnosis

• Augmentation index findings

• Echocardiography-derived arterial stiffness markers

• MRI-based arterial elasticity evaluation

• Arterial tonometry results

• Findings in vascular ultrasound related to stiffness

• Novel or experimental diagnostic approaches

3. Clinical Presentations

• Isolated systolic hypertension

• Early vascular aging in young patients

• Aortic stiffness leading to LV hypertrophy

• Heart failure with preserved ejection fraction (HFpEF) associated with stiffness

• Cerebrovascular symptoms secondary to arterial stiffness

• Peripheral vascular stiffness with claudication symptoms

• Rare severe stiffness cases with multi-organ implications

4. Complications

• Aortic aneurysm / dissection risk associated with stiffness

• Accelerated coronary artery disease

• Stroke and cognitive impairment linked to vascular stiffness

• Microvascular ischemia

• Arterial calcification progression

5. Management and Treatment Insights

• Pharmacologic approaches (ACE inhibitors, ARBs, calcium channel blockers)

• Lifestyle and dietary interventions

• Management of reversible causes

• Vascular rehabilitation or exercise-based improvements

• Novel therapies in research settings

• Follow-up demonstrating improvement or progression

Manuscript Submission
Authors are requested to submit their manuscript by using Online Manuscript Submission Portal: https://www.casereportsincardiology.org/submit.html (or) also invited to submit through the Journal E-mail Id: editor@casereportsincardiology.org.